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Updated: Jan 23, 2026

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments
Published on: November 12, 2019
Neural activity of heterogeneous inhibitory spiking networks with delay
Stefano Luccioli1, David Angulo-Garcia2, Alessandro Torcini1,3
1CNR-Consiglio Nazionale delle Ricerche-Istituto dei Sistemi Complessi, via Madonna del Piano 10, 50019 Sesto Fiorentino, Italy.
Abstract:
We study a network of spiking neurons with heterogeneous excitabilities connected via inhibitory delayed pulses. For globally coupled systems the increase of the inhibitory coupling reduces the number of firing neurons by following a winner-takes-all mechanism. For sufficiently large transmission delay we observe the emergence of collective oscillations in the system beyond a critical coupling value. Heterogeneity promotes neural inactivation and asynchronous dynamics and its effect can be counteracted by considering longer time delays. In sparse networks, inhibition has the counterintuitive effect of promoting neural reactivation of silent neurons for sufficiently large coupling. In this regime, current fluctuations are on one side responsible for neural firing of subthreshold neurons and on the other side for their desynchronization. Therefore, collective oscillations are present only in a limited range of coupling values, which remains finite in the thermodynamic limit. Out of this range the dynamics is asynchronous and for very large inhibition neurons display a bursting behavior alternating periods of silence with periods where they fire freely in absence of any inhibition.
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