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Naloxone and naltrexone. Application in COPD
1Ingalls Memorial Hospital, Harvey, Illinois.
Abstract:
The narcotic antagonists naloxone and naltrexone were used as respiratory stimulants in two patients failing traditional medical therapy for COPD. Both patients demonstrated improvement while receiving the drugs, but developed respiratory failure when they were discontinued abruptly. In selected patients with COPD, narcotic antagonists may offer an additional mode of therapy.
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