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Late-course accelerated hyperfractionated intensity-modulated radiotherapy for nasopharyngeal adenoid cystic
Dehuan Xie1, Aoqiang Chen1, Shaowen Lv1
1Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.
Abstract:
Nasopharyngeal adenoid cystic carcinoma is a rare neoplasm characterized by strong local invasiveness and a higher tendency to relapse. Because of the rare cases, there is a little consensus on treatment. We report a case of T3N0 NACC with a positive resection margin treated with postoperative adjuvant radiotherapy. MRI reexamination indicated suspected tumor progression during the course of radiotherapy. In order to improve local control, late-course accelerated hyperfractionated intensity-modulated radiotherapy (LCAF-IMRT) was performed to escalate total dose, which achieved good local control with no significant late toxicity.
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