Takotsubo cardiomyopathy-like phenotype in a boy
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Updated: Jan 23, 2026

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Published on: November 29, 2024
Mohammed Firdouse1, Arnav Garwal1, Claudia Lace De Almeida2
1Faculty of Health Sciences, McMaster Children's Hospital, McMaster University, Hamilton, ON, Canada.
Insights
Takotsubo cardiomyopathy, a stress-induced heart condition, was observed in a child post-tonsillectomy. This rare pediatric case highlights potential triggers and recovery in young patients.
Area of Science:
- Pediatric Cardiology
- Cardiovascular Research
- Critical Care Medicine
Background:
- Takotsubo cardiomyopathy (TTC) typically presents in adults following significant emotional or physical stress.
- Pediatric cases of TTC are rare, with limited understanding of its triggers and clinical course in children.
Observation:
- A 4-year-old boy developed symptoms mimicking TTC after tonsillectomy and adenoidectomy.
- Clinical presentation included cyanosis, dyspnea, altered consciousness, and echocardiographic findings of left ventricular hypokinesia and apical ballooning.
Findings:
- The child received hemodynamic support with inotropes and diuretics.
- Cardiac function normalized within 3-4 weeks, with complete recovery and no residual abnormalities upon follow-up.
Implications:
- Post-tonsillectomy complications such as myocarditis, rhabdomyolysis, or sepsis may act as stressors for TTC in children.
- This case underscores the importance of considering TTC in pediatric patients presenting with acute cardiac dysfunction after stressful events.
- Further research is warranted to elucidate the pathophysiology and management of TTC in pediatric populations.
Abstract:
Takotsubo cardiomyopathy is characterized by the acute onset of a reversible left ventricular wall motion abnormality that extends beyond a single coronary artery's distribution, following a period of emotional or physical stress. We present a 4 yr 11 mo old boy who was admitted to the pediatric intensive care unit a few days following tonsillectomy and adenoidectomy. The patient presented with mild cyanosis, shortness of breath and decreased levels of consciousness. Initial investigations revealed significant hypokinesia and dilatation of the mid and apical segments of the left ventricle along with preserved function of the basal segment. The patient was given inotropes and diuretics for hemodynamic management. The patient made a complete recovery with normalization of cardiac function within 3-4 wk. Upon follow up, the patient had normal sinus rhythm, improved ejection fraction and no ventricular wall motion abnormalities. The authors believe the myocarditis, rhabdomyolysis, and sepsis following tonsillectomy and adenoidectomy to be the stressors in this case. The rarity of cases that phenotypically mimic classical Takotsubo cardiomyopathy in children makes this case of special interest to pediatricians and cardiologists.
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