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Related Experiment Video

Updated: Jan 23, 2026

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

Published on: September 10, 2014

Electric and Electrochemical Microfluidic Devices for Cell Analysis.

Kaoru Hiramoto¹, Kosuke Ino², Yuji Nashimoto^2,3

¹Graduate School of Environmental Studies, Tohoku University, Sendai, Japan.

Frontiers in Chemistry

|June 20, 2019

Summary

Electric and electrochemical systems integrated into microfluidic devices enhance cell analysis. This review covers advances in cell manipulation, assays, and component collection for applications from single cells to organs-on-a-chip.

Keywords:

cell analysis cell manipulation electric devices electrochemical devices microfluidic devices organs-on-a-chip

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Published on: November 17, 2021

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Last Updated: Jan 23, 2026

A Microfluidic-based Electrochemical Biochip for Label-free DNA Hybridization Analysis

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Published on: September 10, 2014

Thermal Measurement Techniques in Analytical Microfluidic Devices

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Co-culture of Glutamatergic Neurons and Pediatric High-Grade Glioma Cells Into Microfluidic Devices to Assess Electrical Interactions

Co-culture of Glutamatergic Neurons and Pediatric High-Grade Glioma Cells Into Microfluidic Devices to Assess Electrical Interactions

Published on: November 17, 2021

Area of Science:

Bioengineering
Analytical Chemistry
Cell Biology

Background:

Microfluidic devices are essential tools for cell analysis, healthcare, and environmental monitoring.
Integrating electric and electrochemical systems into microfluidics enables high-throughput, real-time, and non-invasive cell assays.

Purpose of the Study:

To review recent advancements in electric and electrochemical systems within microfluidic devices.
To explore applications ranging from single-cell analysis to organs-on-a-chip.
To highlight future research directions and application prospects in this field.

Main Methods:

Summarizing microfluidic devices utilizing dielectrophoresis, electrophoresis, and electrowetting-on-a-dielectric for cell manipulation.
Reviewing electric and electrochemical assays for cell activity, including chemical activity, oxygen, and glucose consumption.
Discussing devices for electric and electrochemical collection of cellular components.

Main Results:

Recent progress has been made in combining microfluidics with electrical techniques for sophisticated cell analysis.
Applications span diverse areas, including precise cell manipulation, detailed cellular activity monitoring, and component isolation.
The integration facilitates advanced studies on single cells, 3D cell cultures, and organ-on-a-chip models.

Conclusions:

Electric and electrochemical microfluidic systems offer powerful capabilities for cell analysis and manipulation.
These integrated systems are crucial for developing advanced biological assays and mimicking organ functions.
The field shows significant promise for future innovations in cell biology, diagnostics, and therapeutic development.