A case report of ectopic pancreatitis in an isolated enteric duplication cyst

Yoshikazu Tanaka1, Go Nakai2, Hideki Tomiyama3

  • 1Department of Radiology, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka, Japan. rad110@osaka-med.ac.jp.

BMC Surgery
|June 20, 2019
PubMed
Abstract

Insights

A rare case of ectopic pancreatitis within an isolated enteric duplication cyst was diagnosed in a child presenting with abdominal pain. This highlights the importance of considering ectopic pancreatitis even with a normal-appearing pancreas.

Area of Science:

  • Gastroenterology
  • Pediatric Surgery
  • Surgical Pathology

Background:

  • Isolated enteric duplication cysts are rare congenital anomalies with their own blood supply.
  • Meckel's diverticulum, typically antimesenteric, can rarely occur on the mesenteric side.
  • Ectopic pancreatic tissue can be associated with both duplication cysts and Meckel's diverticulum.

Observation:

  • A 5-year-old girl presented with umbilical pain, elevated pancreatic enzymes, and C-reactive protein.
  • CT revealed a mesenteric cystic lesion separate from a normal pancreas, with an enhancing nodule.
  • Laparoscopy confirmed a mesenteric lesion distant from the ileum, which was resected.

Findings:

  • Pathology showed the cyst wall resembled small bowel, with ectopic pancreatic tissue beneath the mucosa.
  • Retrospective CT identified an independent blood supply to the cyst.
  • The final diagnosis was ectopic pancreatitis within an ileal duplication cyst.

Implications:

  • This case underscores the diagnostic challenges of isolated enteric duplication cysts and mesenteric Meckel's diverticulum.
  • Elevated pancreatic enzymes in the presence of a normal pancreas warrant consideration of ectopic pancreatitis.
  • Accurate diagnosis is crucial for appropriate management of these rare congenital anomalies.

Related Concept Videos

Centrosome Duplication02:25

Centrosome Duplication

The primary microtubule organizing center (MTOC) in animal cells is the centrosome. A centrosome has two cylindrical centrioles at its core. Each centriole consists of nine sets of three microtubules held together by proteins. The centrioles are positioned at right angles to each other and surrounded by a shapeless protein cloud called the pericentriolar matrix, or pericentriolar material (PCM).
To ensure that each daughter cell receives a centrosome after cell division, centrosome duplication...
4.9K
Gene Duplication and Divergence02:37

Gene Duplication and Divergence

The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are...
7.9K
Duplication of Chromatin Structure02:05

Duplication of Chromatin Structure

The process of chromosome duplication during cell division requires genome-wide disruption and re-assembly of chromatin. The chromatin structure must be accurately inherited, reassembled, and maintained in the daughter cells to ensure lineage propagation.
The basic unit of the chromatin is the nucleosome, consisting of DNA wrapped around octameric histone proteins and short stretches of linker DNA separating individual nucleosomes. The histone proteins within the nucleosome have their...
7.2K
Data Reporting and Recording01:24

Data Reporting and Recording

Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.4K