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Updated: Jan 23, 2026

Estimation of Nephron Number in Whole Kidney using the Acid Maceration Method
Published on: May 22, 2019
My Bleeding Nephrons!
Jiemin Li1, Sandeep Anand Padala2, George Hinnant2
11 Medical College of Georgia, Augusta, GA, USA.
Abstract:
Anticoagulation-related nephropathy (ARN) is an uncommon diagnosis that should be considered in patients presenting with unexplained acute kidney injury (AKI) and coagulopathy. In this article, we present the case of a 70-year-old male with a history of cirrhosis and portal vein thrombosis on Coumadin who presented to the hospital with gross hematuria. The patient was diagnosed with AKI on chronic kidney disease (CKD) secondary to ARN superimposed on sclerosing IgA nephropathy. ARN, also known as warfarin-associated nephropathy, is an uncommon condition in which AKI from glomerular hemorrhage develops in a patient with an international normalized ratio greater than 3. The most common risk factor for development of ARN is CKD. AKI in our patient unearthed preexisting CKD due to IgA nephropathy as evidenced by the biopsy.
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