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Updated: Jan 23, 2026

Quantifying Yersinia pseudotuberculosis Type III Secretion System Activity Following Iron Starvation and Anaerobic Growth
Published on: May 31, 2024
Export Mechanisms and Energy Transduction in Type-III Secretion Machines
Thibaud T Renault1,2,3,4, Alina Guse1, Marc Erhardt5
1Institute for Biology-Bacterial Physiology, Humboldt-Universität zu Berlin, Berlin, Germany.
Abstract:
The remarkably complex architecture and organization of bacterial nanomachines originally raised the enigma to how they are assembled in a coordinated manner. Over the years, the assembly processes of the flagellum and evolutionary-related injectisome complexes have been deciphered and were shown to rely on a conserved protein secretion machine: the type-III secretion system. In this book chapter, we demonstrate how individually evolved mechanisms cooperate in highly versatile and robust secretion machinery to export and assemble the building blocks of those nanomachines.
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