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Related Concept Videos

Model Approaches for Pharmacokinetic Data: Compartment Models01:14

Model Approaches for Pharmacokinetic Data: Compartment Models

542
Compartmental analysis is a widely adopted approach to characterizing drug pharmacokinetics. It uses compartment models that conceptualize the body as a collection of reversibly communicating compartments, each representing a group of tissues exhibiting similar drug distribution characteristics. The movement rate of the drug between these compartments is typically described by first-order kinetics.
Two primary types of compartment models are recognized: mammillary and catenary. The more...
542
Model Approaches for Pharmacokinetic Data: Physiological Models01:15

Model Approaches for Pharmacokinetic Data: Physiological Models

252
Physiological models in pharmacokinetics are instrumental in understanding the distribution and elimination of drugs within the body. These models describe the drug concentration within target organs, influenced by factors such as drug uptake, tissue volume, and blood flow. Drug uptake is governed by the partition coefficient, which signifies the drug concentration ratio in tissue to that in the blood. The blood flow rate to a specific tissue is expressed as Qt, and the rate of change in tissue...
252
Model-Independent Approaches for Pharmacokinetic Data: Noncompartmental Analysis00:59

Model-Independent Approaches for Pharmacokinetic Data: Noncompartmental Analysis

327
Noncompartmental analyses offer an alternative method for describing drug pharmacokinetics without relying on a specific compartmental model. In this approach, the drug's pharmacokinetics are assumed to be linear, with the terminal phase log-linear. This assumption allows for simplified analysis and interpretation of the drug's behavior in the body.
One important characteristic of noncompartmental analyses is that drug exposure increases proportionally with increasing doses. This...
327
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models01:06

Model Approaches for Pharmacokinetic Data: Distributed Parameter Models

244
Pharmacokinetic models are mathematical constructs that represent and predict the time course of drug concentrations in the body, providing meaningful pharmacokinetic parameters. These models are categorized into compartment, physiological, and distributed parameter models.
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
244
Analysis Methods of Pharmacokinetic Data: Model and Model-Independent Approaches01:14

Analysis Methods of Pharmacokinetic Data: Model and Model-Independent Approaches

506
Drug disposition in the body is a complex process and can be studied using two major approaches: the model and the model-independent approaches.
The model approach uses mathematical models to describe changes in drug concentration over time. Pharmacokinetic models help characterize drug behavior in patients, predict drug concentration in the body fluids, calculate optimum dosage regimens, and evaluate the risk of toxicity. However, ensuring that the model fits the experimental data accurately...
506
Reducing Line Loss01:18

Reducing Line Loss

371
In a three-phase circuit, line loss is an indicator of energy dissipated as heat due to the resistance of transmission lines. To address this, incorporating transformers into the system—a step-up transformer at the source and a step-down transformer at the load—is a strategic solution. Two three-phase transformers are introduced to improve this.
With a step-up transformer at the source, the voltage is increased, thereby reducing the current in the transmission lines since power loss in...
371

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A Data-Driven Approach to Quantifying Immune States in Sepsis
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Reduced Time Compression in Big Data Using MapReduce Approach and Hadoop.

K Meena1, J Sujatha2

  • 1Department of Computer Science & Engineering, Vel Tech Rangarajan Dr. Sagunthala R&D Institute of Science and Technology, Chennai, India. meen.nandhu@gmail.com.

Journal of Medical Systems
|June 21, 2019
PubMed
Summary
This summary is machine-generated.

This study introduces a novel approach using the MapReduce framework and Co-Effective and Adaptive Neuro-Fuzzy System (Co-EANFS) for efficient big data classification and prediction in agriculture. The proposed model enhances crop production insights by integrating climate data and optimizing data processing with reduced execution time.

Keywords:
Association rule miningBig dataClassificationClusteringCo-effective and adaptive neuro-fuzzy system (Co-EANFS)HadoopMapReducePrediction

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Area of Science:

  • Data Science
  • Artificial Intelligence
  • Agricultural Science

Background:

  • Exponential growth in real-time data volume necessitates efficient processing techniques.
  • Classification of big data is a complex and time-consuming task.
  • Integrating climatological and meteorological data with farming decisions presents challenges.

Purpose of the Study:

  • To propose a MapReduce-based framework for processing heterogeneous big data.
  • To enhance climate classification and prediction using the Co-Effective and Adaptive Neuro-Fuzzy System (Co-EANFS).
  • To examine association rule mining for optimizing crop production based on soil and weather conditions.

Main Methods:

  • Utilized the MapReduce framework for parallel data processing and distribution.
  • Employed the Co-Effective and Adaptive Neuro-Fuzzy System (Co-EANFS) for empirical climate classification and prediction.
  • Implemented association rule mining to identify optimal crop production strategies.
  • Developed a technique for managing data preprocessing, clustering, classification, and prediction levels.

Main Results:

  • The proposed model effectively processes weather datasets, forming seasonal cluster datasets.
  • Co-EANFS demonstrated accurate predictions with varying inputs and variables.
  • The framework achieved minimal execution time, indicating high efficiency.

Conclusions:

  • The integrated MapReduce and Co-EANFS framework offers an efficient solution for big data challenges in agriculture.
  • The approach provides valuable insights for crop production by linking climate data with farming decisions.
  • The proposed technique successfully manages multiple data processing stages, leading to optimized outcomes.