Related Experiment Video
Updated: Jan 23, 2026

Training Persons with Spinal Cord Injury to Ambulate Using a Powered Exoskeleton
Published on: June 16, 2016
Elucidating the Role of Apolipoprotein E Isoforms in Spinal Cord Injury-Associated Neuropathology
Carlos A Toro1,2, Dibash K Das1,2, Dongming Cai3,4
1National Center for the Medical Consequences of Spinal Cord Injury, James J. Peters VA, Bronx, New York.
Abstract:
Spinal cord injury (SCI) is a devastating, life-altering, neurological event that affects ∼300,000 individuals in the United States. Currently, there are no effective treatments to reverse the neurological impairments caused by the lesion. Until a cure is available, there is an urgent need for strategies that can either spare injured neurons or promote neuroplasticity and functional recovery. Genetic links to outcomes after SCI may provide insights into the pathological mechanisms, and possible new avenues for drug development. In the present review, we discuss the current knowledge linking apolipoprotein E genotypes with better or worse functional outcomes after an SCI, and the possible molecular mechanisms that may contribute to this association.
Related Concept Videos
Spinal Cord
The Spinal Cord
Spinal Cord: Information Processing
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Spinal Cord: Gross Anatomy
Spinal Cord: Cross-sectional Anatomy
Gray Matter and its Components
Central to the gray matter is...
The Role of Culture

