Related Experiment Video
Updated: Jan 23, 2026
12:42
Photoactivated Localization Microscopy with Bimolecular Fluorescence Complementation BiFC-PALM
Published on: December 22, 2015
10.3K
Hypokeratotic lesion on the palm
Clemens Schöffl1, Lukas Koch1, Lorenzo Cerroni1
1Department of Dermatology, Medical University of Graz, Austria.
Summary
No abstract available in PubMed .
Related Concept Videos
02:10Translesion DNA Polymerases
11.1K
Translesion (TLS) polymerases rescue stalled DNA polymerases at sites of damaged bases by replacing the replicative polymerase and installing a nucleotide across the damaged site. Doing so, TLS allows additional time for the cell to repair the damage before resuming regular DNA replication.
TLS polymerases are found in all three domains of life - archaea, bacteria, and eukaryotes. Of the different classes of TLS polymerases, members of the Y family are fitted with specialized structures that...
TLS polymerases are found in all three domains of life - archaea, bacteria, and eukaryotes. Of the different classes of TLS polymerases, members of the Y family are fitted with specialized structures that...
11.1K
01:08Nucleotide Excision Repair
40.6K
Overview
40.6K
02:37Restarting Stalled Replication Forks
6.3K
DNA replication is initiated at sites containing predefined DNA sequences known as origins of replication. DNA is unwound at these sites by the minichromosome maintenance (MCM) helicase and other factors such as Cdc45 and the associated GINS complex.The unwound single strands are protected by replication protein A (RPA) until DNA polymerase starts synthesizing DNA at the 5’ end of the strand in the same direction as the replication fork. To prevent the replication fork from falling apart,...
6.3K