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Chronic inflammatory liver diseases and coffee intake
Franco Contaldo1, Lidia Santarpia, Fabrizio Pasanisi
1Internal Medicine and Clinical Nutrition Unit, Interuniversity Center for Obesity and Eating disorders (CISRO), Department of Clinical Medicine and Surgery, Federico II University Hospital, Naples, Italy.
Coffee consumption offers protective benefits against metabolic diseases and certain cancers, particularly for liver health. Its compounds provide antioxidant and anti-inflammatory effects, supporting liver function and potentially preventing conditions like fibrosis and cirrhosis.
Area of Science:
- Nutritional Science
- Gastroenterology
- Oncology
Background:
- Coffee contains various bioactive compounds, including caffeine, polyphenols, and diterpenes.
- These components possess antioxidant and anti-inflammatory properties.
- Previous research suggests coffee's potential role in mitigating metabolic diseases and cancer risks.
Purpose of the Study:
- To review the protective effects of coffee on metabolic health.
- To focus on the preventive and therapeutic actions of coffee concerning liver function.
- To explore coffee's role in combating liver diseases and cancer.
Main Methods:
- This study is a literature review.
- It synthesizes findings on coffee's impact on liver enzymes and fibrosis.
- It examines the mechanisms behind coffee's health benefits.
Main Results:
- Coffee consumption demonstrates protective effects against metabolic diseases and some cancers.
- Polyphenols in both caffeinated and decaffeinated coffee show benefits for liver fibrosis and enzyme levels.
- Diterpenes contribute to detoxification and antioxidant activity, benefiting liver health and potentially preventing cirrhosis and cancer.
Conclusions:
- Regular coffee consumption, especially without added sugar, may offer preventive health benefits.
- Coffee intake should not be restricted for individuals with chronic inflammatory liver diseases, including hepatocellular carcinoma.
- Coffee's multifaceted components contribute to its protective effects on liver health.
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