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Quantification of Mouse Heart Left Ventricular Function, Myocardial Strain, and Hemodynamic Forces by Cardiovascular Magnetic Resonance Imaging
Published on: May 24, 2021
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Imaging and heart failure: myocardial strain.
Thor Edvardsen1,2, Lars Gunnar Klaeboe1,2
1Department of Cardiology and Center for Cardiological Innovation, Oslo University Hospital, Rikshospitalet.
Current Opinion in Cardiology
|June 21, 2019
Summary
Myocardial strain imaging offers crucial prognostic insights for heart failure patients. Further research is needed to standardize techniques like right ventricular (RV) and left atrial (LA) strain for broader clinical adoption.
Area of Science:
- Cardiology
- Medical Imaging
- Echocardiography
Background:
- Heart failure (HF) management relies on accurate prognostic indicators.
- Myocardial strain imaging has emerged as a valuable tool in assessing cardiac function.
- Recent advancements focus on expanding strain analysis beyond the left ventricle.
Purpose of the Study:
- To review the literature on myocardial strain applications in heart failure since 2018.
- To highlight the prognostic value of left ventricular (LV) and right ventricular (RV) strain.
- To explore novel applications of atrial strain and myocardial work estimation.
Main Methods:
- Systematic literature review of studies published from 2018 onwards.
- Analysis of research focusing on echocardiographic myocardial strain parameters.
- Inclusion of studies investigating LV, RV, and left atrial (LA) strain, as well as myocardial work.
Main Results:
- LV and RV strain provide significant prognostic information in acute and chronic heart failure.
- Atrial strain may enhance the detection of diastolic dysfunction.
- Myocardial work estimation offers new insights into LV performance and potential therapy selection.
Conclusions:
- Myocardial strain is increasingly linked to adverse outcomes in heart failure.
- Global Longitudinal Strain (GLS) is nearing clinical readiness.
- Standardization of RV strain, LA strain, and myocardial work is essential for widespread clinical implementation.
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