Antibiotic prescribing for tonsillopharyngitis in a general practice setting: Can the use of Modified Centor Criteria

Chirag Patel1, Benjamin Daniel Green2, Jacynta May Batt3

  • 1MPharm (Hons), MBBCh, Cert EM (ACEM), FRACGP, Clin Dip Pall Med (RACP), Consultant Primary Care Physician, Flinders University, SA.

Abstract

Insights

Documenting Modified Centor Criteria (MCC) for sore throat consultations is linked to reduced antibiotic prescribing. This practice may improve patient safety and lower unnecessary antibiotic use, combating antimicrobial resistance.

Area of Science:

  • General Practice
  • Infectious Disease
  • Antimicrobial Stewardship

Background:

  • Antibiotic prescribing for sore throat aims to prevent Group A Streptococcus complications.
  • Antimicrobial resistance necessitates careful antibiotic stewardship.
  • Tonsillopharyngitis treatment requires evaluation of clinical criteria.

Purpose of the Study:

  • To investigate antibiotic prescribing patterns for tonsillopharyngitis.
  • To assess the relationship between Modified Centor Criteria (MCC) documentation and antibiotic prescribing.
  • To evaluate the impact of documentation on appropriate antibiotic use.

Main Methods:

  • Retrospective analysis of consultation records from two rural Australian general practices.
  • Identification of tonsillopharyngitis cases using keyword searches in clinic management software.
  • Statistical analysis to correlate MCC documentation with antibiotic prescribing rates.

Main Results:

  • Antibiotic prescribing for tonsillopharyngitis was frequent.
  • Documented evidence of MCC components was associated with significantly lower antibiotic prescribing (77.7% vs. 85.5%, P <0.001).
  • The odds of prescribing antibiotics were lower when MCC criteria were documented (OR: 2.4, 95% CI: 1.8–3.3).

Conclusions:

  • This study is the first to correlate documentation of MCC with antibiotic prescribing for tonsillopharyngitis.
  • Adopting and documenting MCC in clinical practice can lead to more appropriate antibiotic prescriptions.
  • Improved documentation may enhance patient safety and significantly reduce antibiotic prescription rates, aiding antimicrobial stewardship.

Related Concept Videos

Antibiotic Selection00:57

Antibiotic Selection

Overview
59.6K
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.4K
Criteria for Causality: Bradford Hill Criteria - II01:28

Criteria for Causality: Bradford Hill Criteria - II

The Bradford Hill criteria serve as guidelines for establishing causative links in epidemiological research. Beyond Strength, Consistency, Specificity, and Temporality, key criteria also include Biological Gradient, Plausibility, Coherence, Experiment, and Analogy. These principles assist scientists in assessing the likelihood of causation in complex biological contexts. Below is a summary of these concepts:
1.2K
Criteria for Causality: Bradford Hill Criteria - I01:30

Criteria for Causality: Bradford Hill Criteria - I

The Bradford Hill criteria are a group of principles that provide a framework to determine a causal relationship between a specific factor and a disease. There are nine criteria that are pivotal in assessing causality in epidemiological studies. Here's a closer look at Strength, Consistency, Specificity, and Temporality criteria with definitions and examples:
1.1K
Reducing Line Loss01:18

Reducing Line Loss

In a three-phase circuit, line loss is an indicator of energy dissipated as heat due to the resistance of transmission lines. To address this, incorporating transformers into the system—a step-up transformer at the source and a step-down transformer at the load—is a strategic solution. Two three-phase transformers are introduced to improve this.
With a step-up transformer at the source, the voltage is increased, thereby reducing the current in the transmission lines since power loss in...
371
Yield Criteria for Ductile Materials under Plane Stress01:25

Yield Criteria for Ductile Materials under Plane Stress

In designing structural elements and machine parts using ductile materials, it is crucial to ensure that these components withstand applied stresses without yielding. Yielding is initially determined through a tensile test, which evaluates the material's response to uniaxial stress. However, tensile stress is insufficient when components face biaxial or plane stress conditions This condition requires advanced criteria to predict failure.
The Maximum Shearing Stress Criterion, also known as...
495