Transvenous Lead Extraction in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy

Amr F Barakat1, Mohammad A Zmaili2, Khaldoun G Tarakji3

  • 1Department of Medicine, Cleveland Clinic, Cleveland, Ohio; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Insights

Transvenous lead extraction (TLE) in arrhythmogenic right ventricular cardiomyopathy (ARVC) patients is safe and effective. High success rates and low complication rates were observed when using established techniques and tools in a high-volume center.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Arrhythmogenic right ventricular cardiomyopathy (ARVC) necessitates device implantation for sudden death prevention.
  • Transvenous lead extraction (TLE) in ARVC patients presents unique challenges due to potential right ventricular wall thinning and fragility.
  • Limited data exists on the safety and efficacy of TLE in the context of ARVC.

Purpose of the Study:

  • To evaluate the effectiveness and safety of transvenous lead extraction (TLE) in patients diagnosed with arrhythmogenic right ventricular cardiomyopathy (ARVC).

Main Methods:

  • A retrospective analysis of consecutive ARVC patients who underwent TLE between 1996 and 2016.
  • Utilized specialized extraction tools with sheaths advanced to the right ventricle with countertraction at the lead tip.
  • Success and complication rates were assessed according to Heart Rhythm Society guidelines.

Main Results:

  • Twenty-two TLE procedures were performed on 27 leads (22 defibrillators, 5 pacemakers) in ARVC patients.
  • Indications for TLE included lead malfunction (77%) and device infection (23%).
  • Complete procedural success was achieved in all cases with no major complications, utilizing specialized tools in 91% of procedures.

Conclusions:

  • Transvenous lead extraction in ARVC patients can be performed with high success and low complication rates.
  • Adherence to guideline-established techniques and utilization of appropriate tools are crucial for safe TLE in ARVC.
  • High-volume centers can achieve excellent outcomes for TLE in this challenging patient population.
Abstract

Related Concept Videos

Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
502
Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
490
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
440
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
535
Cardiomyopathy VI: Nursing Management01:29

Cardiomyopathy VI: Nursing Management

Assessment: Nursing management of patients with cardiomyopathy begins with a thorough assessment of the patient's history, including a family history of cardiomyopathy or sudden cardiac death, personal history of heart disease, hypertension, diabetes, and any alcohol consumption or drug use.During the physical examination, assess vital signs, look for signs of heart failure (such as edema, jugular venous distention, and cyanosis), auscultate for abnormal heart sounds (like murmurs and gallops),...
326
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
365