Transvenous Lead Extraction in Patients With Arrhythmogenic Right Ventricular Cardiomyopathy
Amr F Barakat1, Mohammad A Zmaili2, Khaldoun G Tarakji3
1Department of Medicine, Cleveland Clinic, Cleveland, Ohio; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Insights
Transvenous lead extraction (TLE) in arrhythmogenic right ventricular cardiomyopathy (ARVC) patients is safe and effective. High success rates and low complication rates were observed when using established techniques and tools in a high-volume center.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) necessitates device implantation for sudden death prevention.
- Transvenous lead extraction (TLE) in ARVC patients presents unique challenges due to potential right ventricular wall thinning and fragility.
- Limited data exists on the safety and efficacy of TLE in the context of ARVC.
Purpose of the Study:
- To evaluate the effectiveness and safety of transvenous lead extraction (TLE) in patients diagnosed with arrhythmogenic right ventricular cardiomyopathy (ARVC).
Main Methods:
- A retrospective analysis of consecutive ARVC patients who underwent TLE between 1996 and 2016.
- Utilized specialized extraction tools with sheaths advanced to the right ventricle with countertraction at the lead tip.
- Success and complication rates were assessed according to Heart Rhythm Society guidelines.
Main Results:
- Twenty-two TLE procedures were performed on 27 leads (22 defibrillators, 5 pacemakers) in ARVC patients.
- Indications for TLE included lead malfunction (77%) and device infection (23%).
- Complete procedural success was achieved in all cases with no major complications, utilizing specialized tools in 91% of procedures.
Conclusions:
- Transvenous lead extraction in ARVC patients can be performed with high success and low complication rates.
- Adherence to guideline-established techniques and utilization of appropriate tools are crucial for safe TLE in ARVC.
- High-volume centers can achieve excellent outcomes for TLE in this challenging patient population.
Objectives:
This study aimed to evaluate the effectiveness and safety of transvenous lead extraction (TLE) in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC).
Background:
ARVC is an increasingly diagnosed cardiomyopathy that often requires device implantation to prevent sudden death. Little is known about TLE in this setting, which has potential challenges and risks, primarily due to right ventricular (RV) wall thinning and fragility.
Methods:
All consecutive patients with ARVC who underwent TLE at our institution between 1996 and 2016 were included. When extraction tools were used, sheaths were advanced to the RV with countertraction at the lead tip. Success and complications were defined in concordance with Heart Rhythm Society guidelines.
Results:
Twenty-two TLE procedures in patients with ARVC involved extraction of 27 leads (22 defibrillators and 5 pacemakers). TLEs were performed due to evidence of lead malfunction (n = 17; 77%) or device infection (n = 5; 23%). Twenty-four leads (89%) were RV, and 3 leads (11%) were right atrial. The median age of the oldest extracted lead was 1,691 days (interquartile range [IQR]: 1,168 to 2,726 days). Specialized extraction tools were required in 20 procedures (91%). None required the use of a snare or a femoral workstation. The median procedural and fluoroscopic times were 152 min (IQR: 129 to 185 min) and 11 min (IQR: 6 to 18 min), respectively. Complete procedural success with removal of all leads was achieved in all cases. There were no major complications.
Conclusions:
In a high-volume center, TLE in patients with ARVC was associated with a high success rate and a low rate of complications when guideline-established techniques and tools were used.
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