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Translatable gene therapy for lung cancer using Crispr CAS9-an exploratory review
Jishnu Nair1, Abhishek Nair1, Soundaram Veerappan1
1Cellular and Molecular Therapeutics Laboratory, Center for Biomaterials, Cellular and Molecular Theranostics, Vellore Institute of Technology, Vellore, Tamil Nadu, 632014, India.
Abstract:
Gene therapy using CRISPR Cas9 technique is rapidly gaining popularity among the scientific community primarily because of its versatility, cost-effectiveness, and high efficacy. While the laboratory-based experiments and findings making use of CRISPR as a gene editing tool are available in ample amounts, the question arises that how much of these findings are actually translatable into measures helping in combating particular disease conditions. In this review, we highlight the important studies and findings done till now in the perspective of lung cancer with an in-depth analysis of various clinical trials associated with the use of CRISPR Cas9 technology in the field of cancer research.
Insights
CRISPR gene editing shows promise for lung cancer treatment. This review analyzes studies and clinical trials exploring CRISPR Cas9 technology
Area of Science:
- Biotechnology
- Genetics
- Oncology
Background:
- CRISPR Cas9 gene editing is a versatile, cost-effective, and highly effective tool.
- Extensive laboratory research exists, but clinical translation remains a key question.
Purpose of the Study:
- To review current findings on CRISPR Cas9 in lung cancer research.
- To analyze clinical trials investigating CRISPR's application in cancer therapy.
Main Methods:
- Literature review of CRISPR Cas9 studies.
- Analysis of clinical trial data for lung cancer applications.
Main Results:
- Highlighting significant studies and findings in lung cancer.
- In-depth analysis of ongoing clinical trials.
Conclusions:
- CRISPR Cas9 technology holds significant potential for lung cancer treatment.
- Further research and clinical trials are crucial for therapeutic development.
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