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Related Experiment Video

Updated: Jan 23, 2026

Retrograde Neuroanatomical Tracing of Phrenic Motor Neurons in Mice
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Transdiaphragmatic Mucormycosis.

Philipp Koehler1,2,3, Robert Reimer4, Roger Wahba5

  • 1Faculty of Medicine, Department I of Internal Medicine, University Hospital of Cologne, University of Cologne.

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|June 22, 2019
PubMed
Summary

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This summary is machine-generated.

Transdiaphragmatic mucormycosis, a rare fungal infection, was identified in 11% of patients. This finding highlights the need for increased clinical awareness and advanced imaging for this potentially underreported condition.

Area of Science:

  • Infectious Diseases
  • Radiology
  • Medical Mycology

Background:

  • Mucormycosis is a severe, often fatal, opportunistic fungal infection.
  • Early diagnosis and treatment are critical for patient survival.
  • Transdiaphragmatic spread represents a less common but significant route of infection.

Purpose of the Study:

  • To report the first series of transdiaphragmatic mucormycosis cases.
  • To determine the incidence of this specific mucormycosis manifestation.
  • To emphasize the importance of comprehensive imaging in mucormycosis diagnosis.

Main Methods:

  • Retrospective case series analysis.
  • Review of patient records and imaging studies.
  • Identification of mucormycosis cases with transdiaphragmatic extension.
Keywords:
isavuconazoleliposomal amphotericin Bposaconazoleradiologyzygomycosis

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Main Results:

  • Three cases of transdiaphragmatic mucormycosis were identified.
  • This phenomenon was observed in 11% of the studied mucormycosis patient cohort.
  • Imaging studies were crucial in diagnosing the extent of infection.

Conclusions:

  • Transdiaphragmatic mucormycosis is an underreported entity in patients with invasive fungal infections.
  • Clinicians must maintain a high index of suspicion for this condition.
  • Enhanced and comprehensive imaging protocols are recommended for mucormycosis patients to detect such spread.