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Updated: Jan 23, 2026

A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
The effects of lower body passive heating combined with mixed-method cooling during half-time on second-half
Jacky Soo1,2, Gabriel Tang3,4, Saravana Pillai Arjunan5
1Sport Physiology, Sport Science and Medicine, Singapore Sport Institute, 3 Stadium Drive, Singapore, 397630, Singapore. jackysds@gmail.com.
Purpose:
This study examined the effects of combined cooling and lower body heat maintenance during half-time on second-half intermittent sprint performances.
Methods:
In a repeated measures design, nine males completed four intermittent cycling trials (32.1 ± 0.3 °C and 55.3 ± 3.7% relative humidity), with either one of the following half-time recovery interventions; mixed-method cooling (ice vest, ice slushy and hand cooling; COOL), lower body passive heating (HEAT), combined HEAT and COOL (COMB) and control (CON). Peak and mean power output (PPO and MPO), rectal (Tre), estimated muscle (Tes-Mus) and skin (TSK) temperatures were monitored throughout exercise.
Results:
During half-time, the decrease in Tre was substantially greater in COOL and COMB compared with CON and HEAT, whereas declines in Tes-Mus within HEAT and COMB were substantially attenuated compared with CON and COOL. The decrease in TSK was most pronounced in COOL compared with CON, HEAT and COMB. During second-half, COMB and HEAT resulted in a larger decrease in PPO and MPO during the initial stages of the second-half when compared to CON. In addition, COOL resulted in an attenuated decrease in PPO and MPO compared to COMB in the latter stages of second-half.
Conclusion:
The maintenance of Tes-Mus following half-time was detrimental to prolonged intermittent sprint performance in the heat, even when used together with cooling.
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