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Updated: Jan 23, 2026

Isolation and Quantification of Zika Virus from Multiple Organs in a Mouse
Published on: August 15, 2019
Central and peripheral nervous system involvement in Zika virus infection in a child
Paula Eillanny Silva Marinho1, Pedro Paulo Martins Alvarenga2,3, Mauricio Teixeira Lima1
1Laboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Antônio Carlos 6627 Caixa, Postal 486, Belo Horizonte, MG, 31270-901, Brazil.
Insights
Zika virus (ZIKV) caused a severe nervous system infection in a child, presenting as encephalomyeloradiculitis without typical arbovirus symptoms. Diagnosis was confirmed through cerebrospinal fluid analysis and neutralization testing.
Area of Science:
- Neurology
- Infectious Diseases
- Virology
Background:
- Arboviruses can cause serious neurological conditions.
- Zika virus (ZIKV) is an emerging arbovirus with potential neurotropic effects.
- Pediatric neurological infections require accurate diagnosis and understanding of causative agents.
Abstract:
A 7-year-old boy that presented an encephalomyeloradiculitis and no classic symptoms of arboviruses. Zika virus (ZIKV) was confirmed by molecular analyses of cerebrospinal fluid and 1 year later by plaque reduction neutralization test. This case demonstrates that ZIKV can be associated with diffuse nervous system infection in children.
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