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Updated: Jan 23, 2026

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma
Published on: April 15, 2022
Unplanned admissions for patients with myeloma in the UK: Low frequency but high costs
Spyros Kolovos1, Guido Nador2, Bhuvan Kishore3
1Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Old Rd, Oxford OX3 7LD, UK.
Background:
Multiple myeloma (MM) is associated with high healthcare resource utilisation and increasing hospitalisation rates. The aim of this study was to characterise the hospital use by patients with MM in the English National Health Service (NHS).
Methods:
Routinely-collected aggregate data about all NHS-funded hospital admissions of patients with MM were analysed. Data were obtained from the English Hospital Episodes Statistics on admissions between 1 April 2014 and 31 March 2018.
Results:
A total of 754,345 admissions were reported over four years, equivalent to a mean of 188,586 admissions per year. Of the 41,845 patients admitted during this period, 42% were women and 58% men. From the total admissions, 90% were elective and 10% unplanned. Mean annual estimated costs over the period were £46 million for elective and £56 million for unplanned admissions. The number of elective admissions increased by 4.5% with costs increasing 1.5% per year; for unplanned admissions, these figures were 4.1% and 9.0%, respectively.
Conclusions:
MM is associated with a significant number of hospital admissions and NHS costs. The majority of the hospital admissions are elective, but the highest burden in terms of costs relates to unplanned admissions, with numbers increasing over time.
Insights
Multiple myeloma (MM) patients incur significant hospital costs, with unplanned admissions being the most expensive. Unplanned admissions are increasing annually, highlighting a growing burden on healthcare resources.
Area of Science:
- Health Services Research
- Oncology
- Health Economics
Background:
- Multiple myeloma (MM) is linked to high healthcare resource use and rising hospital admission rates.
- Understanding hospital utilization patterns is crucial for managing MM patient care.
Purpose of the Study:
- To characterize hospital use among patients with multiple myeloma (MM) within the English National Health Service (NHS).
Main Methods:
- Analysis of aggregate, routinely collected data on all NHS-funded hospital admissions for MM patients.
- Data sourced from English Hospital Episodes Statistics for admissions between April 1, 2014, and March 31, 2018.
Main Results:
- Over four years, 754,345 MM admissions were recorded (mean 188,586/year).
- Elective admissions constituted 90% of total admissions, while unplanned admissions were 10%.
- Annual costs averaged £46 million for elective and £56 million for unplanned admissions, with unplanned admissions showing higher cost increases (9.0% vs. 1.5%).
Conclusions:
- Multiple myeloma (MM) significantly contributes to hospital admissions and NHS expenditures.
- While elective admissions are more frequent, unplanned admissions represent a greater cost burden and are increasing.
- The rising trend in unplanned admissions necessitates targeted strategies for MM patient management and resource allocation.
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