Related Experiment Video
Updated: Jan 23, 2026

Neurocircuit Assays for Seizures in Epilepsy Mutants of Drosophila
Published on: April 15, 2009
Surgical treatment of extra-hypothalamic epilepsies presenting with gelastic seizures
Holger Joswig1, Patricia Rejas-Pinelo2, Ana Suller1
1Epilepsy Program, Department of Clinical Neurological Sciences, London Health Sciences Centre, University Hospital, London, ON, Canada.
Abstract:
We provide an overview of the surgical outcome of extra-hypothalamic epilepsies with gelastic seizures based on an original case report and a summary of the literature. Twenty-two articles providing information on the outcome of resective surgery in 39 patients with extra-hypothalamic gelastic seizures from the temporal (19 patients) or frontal lobe (20 patients) were selected. We add another case of temporal lobe gelastic seizures to the literature with a video demonstrating the mirthful component of this patient's laughing seizures. Drug-refractory cases of gelastic seizures from the temporal or frontal lobes are amenable to surgical treatment following thorough investigation with imaging, as well as scalp and intracranial EEG.
Related Concept Videos
Epilepsy and Seizures: Overview
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Hypothalamic-Pituitary Axis
Seizures: Classification
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Kidney Transplant II: Surgical Procedure
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Alzheimer's Disease: Treatment

