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Emergency department visit count: a practical tool to predict asthma hospitalization in children
Sandra Giangioppo1,2,3, Vid Bijelic4, Nick Barrowman4
1Children's Hospital of Eastern Ontario, Ottawa, ON, Canada.
Insights
The number of emergency department (ED) visits for asthma in children can predict future hospitalizations. More frequent ED visits indicate a higher risk, enabling targeted preventative care.
Area of Science:
- Pediatric Emergency Medicine
- Respiratory Health
- Health Services Research
Background:
- Emergency department (ED) visits for pediatric asthma are common, but resource limitations hinder effective preventative strategies.
- Identifying children at high risk for asthma hospitalization is crucial for targeted interventions.
- Current methods for risk stratification in pediatric asthma are insufficient.
Purpose of the Study:
- To determine if the frequency of emergency department (ED) visits predicts future asthma hospitalizations in children.
- To establish a reliable metric for identifying high-risk pediatric asthma patients.
Main Methods:
- Retrospective analysis of health administrative data for children (2-16.99 years) with asthma ED visits (2012-2015).
- Survival analysis, including Kaplan-Meier and multivariable Cox regression with time-varying covariates.
- Assessed the predictive value of previous year's ED visit count on subsequent year's hospitalization risk, adjusting for age, sex, and severity.
Main Results:
- Identified 2669 children with 3300 asthma-related ED visits.
- ED visit count independently predicted future asthma hospitalizations (p < 0.001) with a dose-dependent relationship.
- Children with one prior ED visit had 2.9 times the hazard of hospitalization; those with two or more had 4.4 times the hazard, compared to those with no prior visits.
Conclusions:
- The number of emergency department (ED) visits serves as a reliable predictor of future asthma hospitalization risk in children.
- ED visit count can be a practical, objective tool for identifying high-risk pediatric asthma patients.
- Findings support the use of ED visit frequency to target preventative interventions for children with asthma.
Abstract:
Objectives: Resource limitations and low rates of follow-up with primary care providers currently limit the impact of emergency department (ED)-based preventative strategies for children with asthma. A mechanism to recognize the children at highest risk of future hospitalization is needed to target comprehensive preventative interventions at discharge. The primary objective of this study was to determine whether frequency of ED visits predicts future asthma hospitalization in children.Methods: Children aged 2-16.99 years with asthma ED visits between 2012 and 2015 were identified through health administrative data. Survival analysis using Kaplan-Meier estimator and multivariable Cox regression models with time-varying covariates were used to quantify the number of ED visits in the previous year that would best predict hospitalization risk in the following year, after adjustment for age, sex, and presentation severity.Results: We identified 2669 patients with 3300 asthma ED visits. ED visit count was an independent predictor of future hospitalization risk (p < 0.001), demonstrating a dose-dependent response. Compared with zero previous visits, the adjusted hazard of future hospitalization in children with one visit or two or more visits was 2.9 (95% CI 1.6-5.0) and 4.4 (95% CI 1.9-10.4), respectively.Conclusions: ED visit count is a reliable predictor of future asthma hospitalization risk. Future studies could aim to validate these findings to support using ED visit count as a practical and objective tool to predict the children at the highest risk of future hospitalization and therefore, those who may benefit most from ED-based preventative interventions.
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Critical processes in asthma pathophysiology include:

