Collagen Matrix for Periodontal Plastic Surgery Procedures: A Meta-analysis Update

Area of Science:

• Periodontology
• Regenerative Dentistry

Background:

• Periodontal plastic surgeries aim to correct soft tissue defects around teeth and implants.
• Collagen matrix (CM) is a potential alternative to autogenous soft tissue grafts.
• Evaluating CM effectiveness is crucial for optimizing treatment outcomes.

Purpose of the Study:

• To systematically review and meta-analyze the effectiveness of collagen matrix (CM) in periodontal plastic surgeries.
• To compare CM with coronally advanced flaps (CAF) and connective tissue grafts (CTG).

Main Methods:

• Systematic review and meta-analysis following PRISMA guidelines.
• Included 14 studies with 1,260 defects in 565 participants.
• Data analyzed using Review Manager 5.3; evidence quality assessed with GRADE.

Main Results:

• CM demonstrated superiority over CAF in mean root coverage (MRC) and keratinized tissue width (KTW).
• Connective tissue graft (CTG) showed better results in complete root coverage (CRC), MRC, and KTW, especially for implants.
• CM showed comparable results to CTG for single gingival recessions but CTG was superior for multiple recessions and long-term outcomes.

Conclusions:

• Collagen matrix (CM) is a viable alternative to soft tissue grafts in periodontal plastic surgery.
• Connective tissue graft (CTG) still offers superior outcomes for specific parameters and defect types.
• Further research may clarify optimal indications for CM in periodontal regeneration.