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    Patient experiences with compounded prescriptions (CRx) show high satisfaction, particularly for hormone replacement therapy and pain management. Prescriber recommendations strongly influence CRx use, though cost remains a concern.

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    Area of Science:

    • Pharmaceutical Sciences
    • Patient-Reported Outcomes
    • Medication Therapy Management

    Background:

    • Limited patient data exists on compounded prescriptions (CRx).
    • Understanding patient initiation and perception of CRx therapy is crucial.

    Purpose of the Study:

    • To investigate how patients initiate compounded prescription (CRx) use.
    • To determine patient perceptions of their CRx therapy.

    Main Methods:

    • A national survey of CRx patients was conducted via mail.
    • Questionnaires assessed demographics, CRx initiation, pharmacy choice, and satisfaction.

    Main Results:

    • Over 494 usable responses were analyzed, predominantly from females (82.3%) aged 60.5 years.
    • Hormone replacement therapy (50.1%) and pain management (23.1%) were primary uses; CRx often replaced prior medications.
    • Patients reported high satisfaction (>95%) with CRx therapy, except for cost, and perceived CRx as effective compared to previous treatments.

    Conclusions:

    • Compounded prescriptions (CRx) are utilized for various conditions, often as alternatives to previous medications due to efficacy or side effects.
    • Prescriber recommendations are key drivers for both CRx adoption and compounding pharmacy selection.
    • While patient satisfaction with CRx therapy is high, out-of-pocket costs present a significant drawback.