A general multi-objective topology optimization methodology developed for customized design of pelvic prostheses

Area of Science:

• Biomedical Engineering
• Materials Science
• Orthopedic Surgery

Background:

• Traditional pelvic prostheses often face challenges with weight, strength, and patient-specific fit.
• Developing patient-specific implants requires advanced design and manufacturing techniques.

Purpose of the Study:

• To formulate and apply a multi-objective topology optimization method for designing pelvic prostheses.
• To create unique prosthetic geometries with enhanced biomechanical properties.

Main Methods:

• A multi-objective topology optimization approach was used, minimizing compliance (maximizing stiffness) while constraining volume.
• Finite element analysis (FEA) was employed to assess implant strength under daily activity loads.
• A patient-specific, topology-optimized hemi-pelvic prosthesis was designed and 3D printed.

Main Results:

• Optimized prosthetic geometries exhibited low weight, high strength, and close matching to pelvic bone anatomy.
• FEA confirmed the optimized implants could withstand static loading conditions with reduced stress concentrations.
• A 3D printed patient-specific prosthesis was successfully implanted in a patient with pelvic sarcoma.

Conclusions:

• Topology optimization enables the design of superior pelvic prostheses with improved biomechanical performance, reduced weight, and increased stiffness.
• Additive manufacturing combined with topology optimization offers efficient production of patient-specific implants.
• Integrating topology optimization into the design of patient-specific pelvic implants is highly recommended for better clinical outcomes.