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TRASE 1D sequence performance in imperfect B1 fields.

Pallavi Bohidar1, Hongwei Sun2, Gordon E Sarty1

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|June 24, 2019
PubMed
Summary
This summary is machine-generated.

Optimizing radio-frequency (RF) magnetic field (B1) phases in Transmit Array Spatial Encoding (TRASE) MRI significantly improves image quality. New TRASE sequences achieve high-quality encoding over 90% of the field-of-view, even with B1 variations.

Keywords:
B(1) inhomogeneityMRIPSFPulse sequence designTRASE

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Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Biophysics
  • Medical Physics

Background:

  • Transmit Array Spatial Encoding (TRASE) utilizes radio-frequency (RF) magnetic field (B1) phase gradients for spatial encoding.
  • TRASE performance is critically dependent on B1 field homogeneity, unlike conventional CPMG sequences.
  • The CPMG condition for B1 error immunity is not applicable to TRASE due to spatially dependent B1 phases.

Purpose of the Study:

  • To investigate the performance of 1D TRASE sequences under B1 inhomogeneity.
  • To optimize TRASE imaging by varying RF waveform phases to improve the point spread function (PSF).
  • To evaluate the impact of B1 errors on TRASE imaging quality.

Main Methods:

  • Simulated 256 variants of 1D TRASE sequences using Bloch equations.
  • Experimentally validated simulation results.
  • Focused solely on B1 inhomogeneity, excluding off-resonance effects.

Main Results:

  • Optimized transmit pulse phases enabled high-quality image encoding across ~90% of the Nyquist field-of-view (FOV).
  • Achieved this performance with practically realizable B1 amplitude variations (Δ|B1| ≤ ±11%).
  • This represents a significant improvement over previous TRASE sequences yielding ~75% usable FOV.

Conclusions:

  • Optimized RF pulse phases are crucial for robust TRASE imaging in the presence of B1 inhomogeneity.
  • The developed TRASE sequences offer enhanced imaging coverage and quality.
  • This advancement has implications for improving MRI spatial encoding techniques.