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Updated: Jan 23, 2026

Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures
Published on: November 22, 2024
Corneal melt secondary to eosinophilic granulomatosis with polyangiitis
Evelyn Fennelly1, Emily Greenan2,3, Conor C Murphy2,3
1Dublin Mid-Leinster Intern Network, Mater Misericordiae University Hospital, Dublin, Ireland.
Abstract:
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare antineutrophil cytoplasmic antibody-associated vasculitis that can affect any organ system. It is most often characterised by chronic airway inflammation along with prominent peripheral blood eosinophilia, although the disease can affect the cardiovascular, gastrointestinal, renal or central nervous systems. Ocular manifestations are uncommon and when they do occur, are varied in their clinical presentations. To the best of our knowledge, this is the first case of corneal melt secondary to EGPA to have been reported.
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