Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Continuous Renal Replacement Therapy01:30

Continuous Renal Replacement Therapy

924
Continuous Renal Replacement Therapy, also known as CRRT, is a procedural treatment for acute kidney injury (AKI) that gradually removes uremic toxins and fluids while maintaining acid-base balance and stabilizing electrolytes. It is particularly useful for hemodynamically unstable patients. Unlike intermittent hemodialysis, which is faster, CRRT provides a gentler approach over 24 hours, closely mimicking the function of natural kidneys. However, CRRT is not ideal for patients with...
924
Types of Hormones02:13

Types of Hormones

83.2K
Hormones can be classified into three main types based on their chemical structures: steroids, peptides, and amines. Their actions are mediated by the specific receptors they bind to on target cells.
83.2K
Types of Hormones01:21

Types of Hormones

6.7K
Hormones are classified into four main groups: steroids, eicosanoids, amino acid-based derivatives, and peptide hormones.
Steroids and eicosanoids fall under the category of lipid-soluble hormones. Steroids are derived from cholesterol and feature four interconnected carbon rings with variable side chains. Notable examples include estradiol from ovaries and testosterone from testes, exemplifying the critical roles of these lipid-soluble hormones in reproductive physiology. Eicosanoids, derived...
6.7K
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy01:26

Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

194
Continuous Renal Replacement Therapy (CRRT) is an essential intervention for patients experiencing severe kidney dysfunction. This therapy offers a continuous mechanism for removing fluids and toxins from the bloodstream, leveraging the patient’s blood pressure to facilitate filtration through a specialized filter. This method contrasts with intermittent dialysis, providing a gentler and more consistent removal of waste products and excess fluid, which is particularly beneficial in...
194
Hormonal Regulation01:33

Hormonal Regulation

35.8K
The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
35.8K
Hormonal Regulation01:40

Hormonal Regulation

47.9K
Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
47.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reconsidering the impairment argument against abortion.

Theoretical medicine and bioethics·2025
Same author

Animal-derived ingredients in medicines: a framework for ethical prescribing practices.

Frontiers in pharmacology·2025
Same author

Public Health, Xenozoonosis, and the Right to Withdraw from Long Term Xenotransplant Biosurveillance.

The New bioethics : a multidisciplinary journal of biotechnology and the body·2025
Same author

Generative AI in healthcare education: How AI literacy gaps could compromise learning and patient safety.

Nurse education in practice·2025
Same author

Artificial intelligence policies in bioethics and health humanities: a comparative analysis of publishers and journals.

BMC medical ethics·2025
Same author

Pilot Survey of Attitudes Toward Xenotransplantation Among Nursing Students in London, UK.

Xenotransplantation·2025
Same journal

Suicide is not a public health issue and perhaps very few things should be.

Journal of medical ethics·2026
Same journal

Not all personal utilities are equal: a two-tier normative framework for genomic health technology assessment.

Journal of medical ethics·2026
Same journal

Emergent ethics of xenotransplantation: findings from a survey on public attitudes toward animal to human organ transplantation in the UK.

Journal of medical ethics·2026
Same journal

Is sport in the 'public interest'? Towards a legal and ethical framework for justifying sport-related harm.

Journal of medical ethics·2026
Same journal

Double standards in the debate on protecting all children from genital cutting: a response to Ahmadu <i>et al</i>.

Journal of medical ethics·2026
Same journal

Fetal and neonatal pain beyond the smoking gun.

Journal of medical ethics·2026
See all related articles

Related Experiment Video

Updated: Jan 23, 2026

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

1.4K

Hormone replacement therapy: informed consent without assessment?

Toni C Saad1, Bruce Philip Blackshaw2, Daniel Rodger3

  • 1Cardiology, University Hospital of Wales Healthcare NHS Trust, Cardiff, UK.

Journal of Medical Ethics
|June 24, 2019
PubMed
Summary
This summary is machine-generated.

Requiring mental health assessment before hormone replacement therapy (HRT) for gender dysphoria is ethically sound. This process aligns with informed consent models and addresses higher rates of psychiatric conditions in transgender individuals.

Keywords:
abortioninformed consentsexuality/gender

More Related Videos

Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay
07:52

Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay

Published on: September 10, 2018

9.2K
Frequent Tail-tip Blood Sampling in Mice for the Assessment of Pulsatile Luteinizing Hormone Secretion
05:58

Frequent Tail-tip Blood Sampling in Mice for the Assessment of Pulsatile Luteinizing Hormone Secretion

Published on: July 4, 2018

15.8K

Related Experiment Videos

Last Updated: Jan 23, 2026

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
06:24

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies

Published on: January 10, 2025

1.4K
Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay
07:52

Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay

Published on: September 10, 2018

9.2K
Frequent Tail-tip Blood Sampling in Mice for the Assessment of Pulsatile Luteinizing Hormone Secretion
05:58

Frequent Tail-tip Blood Sampling in Mice for the Assessment of Pulsatile Luteinizing Hormone Secretion

Published on: July 4, 2018

15.8K

Area of Science:

  • Medical Ethics
  • Transgender Healthcare
  • Psychiatry

Background:

  • Florence Ashley argues against mandatory mental health assessment for gender dysphoria patients seeking hormone replacement therapy (HRT), deeming it unethical.
  • Ashley suggests this requirement may reflect unconscious bias against transgender individuals.

Purpose of the Study:

  • To refute Florence Ashley's claims regarding the ethics of pre-HRT mental health assessments for gender dysphoria.
  • To clarify the distinction between symptom self-reporting and self-diagnosis within the informed consent model.
  • To support the necessity of psychological assessment and referral for transgender patients undergoing HRT.

Main Methods:

  • Critically analyzing Florence Ashley's arguments on informed consent and HRT.
  • Comparing the informed consent model for HRT with that of cosmetic surgery.
  • Reviewing literature on psychiatric morbidity prevalence in the transgender population.

Main Results:

  • Ashley conflates symptom self-reporting with self-diagnosis, deviating from standard informed consent principles.
  • The informed consent model for cosmetic surgery, which Ashley favors, also includes psychological assessment and referral.
  • Elevated psychiatric morbidity rates in transgender individuals support the need for mental health evaluation before HRT.

Conclusions:

  • The requirement for mental health assessment before HRT for gender dysphoria is ethically justified and aligns with established medical practices.
  • This process ensures informed consent and addresses the specific health needs of transgender patients.
  • The findings support the continued use of psychological evaluation as a standard of care in gender-affirming hormone therapy.