Related Experiment Video
Updated: Jan 23, 2026

Analysis of Extracellular Vesicle-Mediated Vascular Calcification Using In Vitro and In Vivo Models
Published on: January 27, 2023
Mechanisms of Matrix Vesicles Mediating Calcification Transition in Diabetic Plaque
Zhongqun Wang1, Lili Zhang1, Zhen Sun1
1Department of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China.
Abstract:
Vascular calcification is a key character of advanced plaque in diabetic atherosclerosis. Microcalcification induces plaque rupture, whereas macrocalcification contributes to plaque stability. However, there is still no clear explanation for the formation and transition of these two types of calcification. Based on existing work and the latest international progress, this article provides a brief review of four aspects: calcification transition in plaque; matrix vesicle-mediated calcification transition in plaque; regulation mechanism of matrix vesicle-mediated calcification transition in diabetic plaque; and proposal of a new hypothesis, which may offer a new perspective on the study of the mechanism of calcification transition in plaque.
More Related Videos
08:43Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
Published on: May 31, 2016
13:45A Method to Study the Correlation Between Local Collagen Structure and Mechanical Properties of Atherosclerotic Plaque Fibrous Tissue
Published on: November 11, 2022
Related Concept Videos
Cell-matrix's Response to Mechanical Forces
Anchoring junctions mechanically attach a cell to the...
Phase Transitions
Properties of Transition Metals
Cooperative Allosteric Transitions
Receptor-mediated Endocytosis
Phase Transitions: Vaporization and Condensation