Related Experiment Video
Updated: Jan 23, 2026
09:09
In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
2.2K
Stop, Listen, and Learn: Using Mixed Methods to Add Value to Clinical Trials
Jennifer Hunter1,2, Mike Armour1
11 Western Sydney University, Sydney, New South Wales, Australia.
Journal of Evidence-Based Integrative Medicine
|June 25, 2019
Summary
Value-based healthcare requires understanding patient experiences alongside outcomes. Integrating mixed methods into clinical trials for traditional, complementary, alternative, and integrative medicine (TCAIM) enhances value assessment and trial quality.
Area of Science:
- Health Services Research
- Clinical Trial Methodology
- Integrative Medicine Research
Background:
- Value-based healthcare emphasizes patient outcomes and experiences.
- Traditional, complementary, alternative, and integrative medicine (TCAIM) research often focuses solely on clinical outcomes.
- Determining the true value of interventions requires a broader perspective.
Purpose of the Study:
- To advocate for the integration of mixed methods study designs in clinical trials.
- To provide a rationale for incorporating patient experiences and preferences into TCAIM research.
- To enhance the assessment of intervention value in healthcare.
Main Methods:
- This is a commentary discussing a conceptual approach.
- It proposes the a priori incorporation of mixed methods into clinical trial designs.
- The focus is on evaluating interventions within the TCAIM field.
Main Results:
- Mixed methods designs can capture both patient outcomes and experiences.
- Integrating qualitative and quantitative data provides a comprehensive understanding of intervention value.
- This approach can improve the quality and relevance of clinical trials.
Conclusions:
- Value-based healthcare necessitates a mixed-methods approach in clinical trials.
- Incorporating patient experiences is crucial for determining the value of TCAIM interventions.
- Mixed methods enhance the rigor and informative nature of clinical research.
Related Concept Videos
01:16Clinical Trials
10.2K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
10.2K
01:11Clinical Trials: Overview
4.6K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
4.6K
01:12Statistical Software for Data Analysis and Clinical Trials
1.4K
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
1.4K
01:12Trial and Error and Algorithm
399
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
399
01:30Mixing Concrete
370
Concrete mixing ensures a homogenous blend where aggregates are well-coated with cement paste. Concrete mixing is typically done using two main types of mixers: batch and continuous. Batch mixers handle one batch at a time, thoroughly combining materials before discharging and receiving the next batch. In contrast, continuous mixers receive a steady flow of ingredients, mixing them consistently and discharging without interruption. Within batch mixers, tilting drum mixers mix with internal...
370
01:19Mixing Time
462
The concept of mixing time is significant in producing a uniform concrete mix with the required strength. The mixing period starts once all components are in the mixer. Initially, the mixer is charged with 10% of the water, followed by the consistent addition of solids and then 80% of the water. The remaining water is added later, within the first quarter of the mixing period. The minimum mixing time varies according to the mixer's capacity; for example, mixers with up to 1 cubic yard...
462