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Nationwide Readmission Rates Following Percutaneous Nephrolithotomy: Does Age Matter?
Ashley W Johnston1, Ruiyang Jiang1, Muhammad H Alkazemi2
1Division of Urology, Duke University Medical Center, Durham, North Carolina.
Insights
Elderly patients undergoing percutaneous nephrolithotomy (PCNL) face higher risks of readmission and complications. Pediatric patients, however, do not show increased risks compared to other age groups for PCNL outcomes.
Area of Science:
- Urology
- Nephrology
- Geriatric Medicine
Background:
- Percutaneous nephrolithotomy (PCNL) is a common procedure for kidney stones.
- Pediatric and elderly patients are often considered high-risk for PCNL morbidity.
- Evidence evaluating age-specific PCNL outcomes is limited.
Purpose of the Study:
- To assess the impact of extreme age (pediatric and elderly) on PCNL readmission and complication rates.
- To compare outcomes across different age groups undergoing PCNL.
- To identify specific age-related risks associated with PCNL.
Main Methods:
- Analysis of Nationwide Readmission Database for PCNL encounters in 2013-2014.
- Categorization of patients into five age groups: pediatric, young adult, adult, geriatric, and elderly.
- Application of weighted logistic regression to evaluate 30-day readmission and complication rates.
Main Results:
- Elderly patients (≥75 years) showed significantly higher odds of 30-day readmission (OR: 7.5) and complications (OR: 68.3) after PCNL.
- Pediatric patients (<18 years) did not exhibit increased odds for readmission or complications compared to other groups.
- While overall GU readmissions were not significantly different for extremes of age, elderly patients faced substantially higher risks.
Conclusions:
- PCNL in elderly patients is associated with significantly increased risks of readmission and postoperative complications.
- PCNL in pediatric patients does not appear to carry elevated risks for readmission or complications.
- Age is a critical factor influencing PCNL outcomes, with the elderly being a particularly vulnerable group.
Abstract:
Despite minimal evidence that evaluates the effect of age on percutaneous nephrolithotomy (PCNL) morbidity, pediatric and elderly patients are considered high-risk groups. Our objective was to assess the effect of the extremes of ages on PCNL readmission and postoperative complication rates. We identified all PCNL encounters in the 2013 and 2014 Nationwide Readmission Database. Encounters were divided into five age groups: pediatric (<18 years old), young adult (18-25 years old), adult (26-64 years old), geriatric (65-74 years old), and elderly (≥75 years old). Weighted descriptive statistics were used to describe population demographics. We fit an adjusted weighted logistic regression model for 30-day readmission and complication rates. We identified 23,357 encounters. Testing average effect of pediatric and elderly encounters to all other age groups did not reveal a difference in odds for 30-day readmissions, but did result in increased odds for 30-day GU readmissions (odds ratio: 17.7 [95% confidence interval (CI): 2.65-118.9]; p = 0.003). Compared to all other age groups, elderly encounters had 7.5 (95% CI: 2.5-22.7; p = 0.0004) times the odds of a 30-day readmission and 68.3 (95% CI: 29.1-160.4; p < 0.0001) times the odds of a postoperative complication. When comparing the average effect of the extremes of ages to all other age groups, we did not find evidence to suggest a difference in odds for 30-day GU readmissions, but did find increased odds for complications. Further examination revealed that PCNL encounters of elderly patients had significantly increased odds for both readmission and complications, whereas PCNL encounters of pediatric patients did not.
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