Visual Hallucinations Induced by Clarithromycin in a Child: A Case Report and Literature Review
1Department of Pediatric Allergy and Immunology, Baskent University Faculty of Medicine.
Insights
A child experienced visual hallucinations after taking oral clarithromycin. Symptoms resolved after discontinuing the antibiotic, suggesting a link to clarithromycin-induced Hoigne syndrome in pediatric patients.
Area of Science:
- Pediatric Neurology
- Pharmacovigilance
- Clinical Toxicology
Background:
- Antibiotic-associated adverse events require careful monitoring.
- Neuropsychological side effects of macrolides are not fully understood.
- Hoigne syndrome is a rare adverse reaction to certain antibiotics.
Objective:
Our aim was to present a child with visual hallucinations possibly associated with oral clarithromycin administration.
Case Report:
A 4-year-old child was admitted to our hospital with an onset of visual hallucinations after taking the second dose of clarithromycin by mouth. The symptoms gradually disappeared in a week once the clarithromycin therapy had been discontinued. She was observed for a month without any symptoms or further treatment. She was suspected of having Hoigne syndrome (also called as antibiomania) induced by clarithromycin syndrome.
Conclusion:
This report highlights neuropsychological adverse effects due to therapeutic doses of clarithromycin therapy as a possible adverse effect in children.
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