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Updated: Jan 23, 2026

Orthotopic Aortic Transplantation: A Rat Model to Study the Development of Chronic Vasculopathy
Published on: December 4, 2010
Successful orthotopic heart transplantation in a patient with Marfan syndrome
Yukihisa Ogawa1, Chun W Choi1, Yasuhiro Shudo1
1Department of Cardiothoracic Surgery, Stanford University School of Medicine, Stanford, California.
Abstract:
Cardiovascular diseases represent the leading cause of mortality in patients with Marfan syndrome. Many treatments have been developed for patients with end-stage heart failure, among which orthotopic heart transplantation remains the gold standard. We report a successful orthotopic heart transplantation for a Marfan syndrome patient in end-stage heart failure.
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