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Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C
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Published on: March 25, 2016

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Transgenerational consequences of maternal immune activation

Daniela D Pollak1, Ulrike Weber-Stadlbauer2

  • 1Department of Neurophysiology and Neuropharmacology, Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.

Seminars in Cell & Developmental Biology
|June 25, 2019
PubMed
Summary

Maternal immune activation during pregnancy can impact brain development and behavior across multiple generations, increasing the risk for neuropsychiatric disorders. Understanding these transgenerational effects is key for new treatments.

Keywords:
AutismMaternal immune activationPoly(I:C)SchizophreniaTransgenerational inheritance

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