Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Sleep in Parkinson's disease.

Ambra Stefani1, Birgit Högl2

  • 1Department of Neurology, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria. ambra.stefani@i-med.ac.at.

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|June 25, 2019
PubMed
Summary

Parkinson's disease disrupts sleep regulation, causing insomnia and daytime sleepiness. It also impairs motor control during sleep, leading to REM sleep behavior disorders and other parasomnias.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Slow-SPEED: protocol for three randomised trials of remotely delivered exercise to prevent Parkinson's disease.

NPJ Parkinson's disease·2026
Same author

Muscle Regeneration Failure May Lead to Clinical Features of Myopathy in Anti-IgLON5 Disease.

Neurology(R) neuroimmunology & neuroinflammation·2026
Same author

CSF turnover dysfunction: a hidden early biomarker in iRBD?

NPJ Parkinson's disease·2026
Same author

Genetic associations between post-traumatic stress disorder and REM-sleep behavior disorder.

NPJ Parkinson's disease·2026
Same author

Machine and deep learning in REM sleep behavior disorder: a scoping review and analysis of reporting quality.

Sleep medicine reviews·2026
Same author

Ru-SATED scale and Sleep Health Index: A systematic review of two leading multidimensional sleep health measures and frameworks across the globe.

Sleep medicine reviews·2026

Area of Science:

  • Neurology
  • Sleep Medicine
  • Movement Disorders

Background:

  • Sleep disturbances are prevalent in Parkinson's disease (PD), encompassing a wide range of sleep disorders.
  • PD affects both the regulation of sleep-wake cycles and motor control during sleep.
  • Common sleep issues include insomnia, excessive daytime sleepiness, and parasomnias like REM sleep behavior disorder (RBD).

Purpose of the Study:

  • To review the spectrum of sleep disorders in Parkinson's disease.
  • To highlight diagnostic challenges, particularly in differentiating sleep disorders from PD symptoms and medication effects.
  • To discuss specific considerations for diagnosing and treating sleep disorders in PD patients.

Main Methods:

  • Literature review of sleep disorders in Parkinson's disease.

Related Experiment Videos

  • Analysis of diagnostic complexities and confounding factors.
  • Discussion of differential diagnosis for common sleep complaints in PD.

    • Main Results:

    • Parkinson's disease is associated with insomnia, daytime sleepiness, and parasomnias (e.g., RBD, sleepwalking).
    • Restless legs syndrome and sleep-related breathing disorders are frequently reported, though their prevalence relative to the general population is debated.
    • Accurate diagnosis is challenging due to overlapping symptoms with PD motor features and medication side effects.

    Conclusions:

    • Sleep disturbances are a significant and multifaceted issue in Parkinson's disease.
    • Careful diagnostic evaluation, including distinguishing mimics and utilizing tools like video-polysomnography for RBD, is crucial.
    • Addressing sleep disorders is essential for comprehensive Parkinson's disease management.