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Updated: Jan 23, 2026

High-throughput Measurement of Gut Transit Time Using Larval Zebrafish
Published on: October 23, 2018
[Development of Koreans Gut Quotient Measurement Scales]
Yoon Jin Choi1, Jae Ho Cho2, Dong Ho Lee2
1Department of Internal Medicine, Korea University Guro Hospital, Seoul, Korea.
Background/Aims:
The aim of this study was to develop 'Koreans Gut Quotient Measurement Scales (GQ)', in which Koreans respond to questionnaires about the subjective feelings and symptoms of their intestinal health status.
Methods:
Among 66 items pooled from previous studies and 4 items that were added following a focus group interview, 15 items were chosen using the Delphi survey. The content validity was evaluated using the content validity ratio. Data collected from 1,120 people from the general public in Korea were analyzed to verify the reliability and validity of GQ.
Results:
The finalized GQ consisted of 17 items (including two exploratory measurement items) that were classified into three independent factors based on exploratory factor analysis (EFA): 'perceived intestine discomfort', 'bowel movement discomfort', and 'bowel movement control discomfort'. The discriminant and convergent validity of GQ were identified using EFA, reliability test, and confirmatory factor analysis. In addition, the criterion-related validity of GQ was identified using correlation and multiple regression analysis.
Conclusions:
The GQ, which is a simplified intestinal health index developed based on an easy questionnaire for the public to understand, can be used as a tool for the public to evaluate their own intestinal health and determine when to visit clinics.
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