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Application of trans-thoracic echocardiography and coronary CT angiography to diagnose mitral valve prolapse

Jingbo Li1, Yun Zhang2, Liulong Zhang2

  • 1Department of Ultrasound, Dongying People's Hospital of Shandong, Dongying, 257091, China.

Journal of Cardiothoracic Surgery
|June 26, 2019
PubMed

Insights

Coronary CT angiography offers superior accuracy in detecting mitral valve prolapse compared to trans-thoracic echocardiography. This advanced imaging technique provides more reliable measurements of mitral valve motion and thickness.

Area of Science:

  • Cardiology
  • Medical Imaging
  • Diagnostic Techniques

Background:

  • Multi-detector cardiac CT is established for assessing heart valve morphology and function.
  • Mitral valve prolapse (MVP) requires accurate diagnostic methods for evaluation.

Purpose of the Study:

  • To compare the diagnostic performance of coronary CT angiography (CCTA) against trans-thoracic echocardiography (TTE) in patients with MVP.
  • To evaluate the accuracy of CCTA in assessing mitral valve leaflet motion and thickness.

Main Methods:

  • CCTA and TTE were utilized to measure the movement range and thickness of the mitral valve leaflets.
  • Ultrasonic parameters from CCTA were considered the reference standard for comparison.

Main Results:

  • CCTA demonstrated high accuracy (95.6%) and sensitivity (69.2%) for detecting mitral valve motion amplitude, with a significant P-value (<0.001).
  • CCTA measurements for mitral leaflet thickness and motion range were (2.00 ± 0.54) mm and (3.76 ± 2.1) mm, respectively.
  • TTE measurements for mitral leaflet thickness and motion range were (1.95 ± 0.22) mm and (1.5 ± 2.28) mm, respectively.

Conclusions:

  • CCTA exhibits higher accuracy and reliability in diagnosing mitral valve prolapse compared to TTE.
  • The findings suggest CCTA is a valuable tool for detailed assessment of MVP.
Abstract

Keywords:
Coronary CT angiographyMitral valve prolapseTrans-thoracic echocardiography

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