The effect of glycemic control on salivary lipid peroxidation in type II diabetic patients
Masoomeh Shirzaiy1, Zohreh Dalirsani2
1Oral and Dental Diseases Research Center, Zahedan University of Medical Science, Zahedan, Iran.
Background And Objective:
Hyperglycemia and some disturbance in antioxidant system lead to free radicals production and oxidative stress. Assessment of some products of oxidative stress could be effective in evaluation of diabetic control. This study aimed at evaluation of glycemic control on salivary lipid peroxidation in diabetic patients.
Methods:
This case control study has been done on 44 diabetic (type II) and 44 healthy subjects. Un-stimulated saliva was collected and correlation between malondialdehid (MDA) as an end -product of lipid peroxidation and HbA1c was assessed.
Results:
MDA and HbA1c of diabetic patients were significantly higher than control group. There was a indirect correlation between MDA and glycemic control level.
Conclusion:
Evaluation of salivary MDA levels could be useful in prediction of glycemic control.
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