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Level of hyperlipidemia in blood donors: A correlative study in North Indian population

Nishat Fatima1, Tulika Chandra1, Abbas Ali Mahdi2

  • 1Department of Transfusion Medicine, King George's Medical University, Lucknow, India; Department of Biotechnology, Dr A.P.J.Abdul Kalam Technical University, U.P, Lucknow, India.

Diabetes & Metabolic Syndrome
|June 26, 2019
PubMed

Insights

Regular blood donation may be associated with lower hyperlipidemia levels. This study found correlations between hyperlipidemia, family history of heart disease, and donor weight in blood donors.

Area of Science:

  • Cardiovascular Health
  • Transfusion Medicine
  • Clinical Biochemistry

Background:

  • Hyperlipidemia, characterized by elevated blood lipids and lipoproteins, is a significant risk factor for heart disease.
  • Factors influencing hyperlipidemia include lifestyle choices and genetic predispositions.
  • Previous observations suggest lower cardiovascular risk markers in regular blood donors compared to first-time donors.

Purpose of the Study:

  • To investigate the impact of blood donation frequency on lipid profiles.
  • To assess the relationship between lipid levels, family history of heart disease, and donor characteristics.

Main Methods:

  • A cross-sectional study involving 80 random blood donors.
  • Analysis of lipid levels and family history of heart disease among single-time and repeat donors.

Main Results:

  • A significant correlation was observed between hyperlipidemic levels and both single-time/repeat donors and donors with a family history of heart disease (p < 0.05).
  • Hyperlipidemia showed a positive association with donor weight (p < 0.05).

Conclusions:

  • Screening blood donors for hyperlipidemia and considering factors like family history, donation frequency, weight, age, and gender can enhance blood supply safety.
  • Implementing stringent donor deferral criteria based on these correlations can improve blood quality and safety guidelines.
Abstract

Keywords:
HyperlipidemiaLDLRepeat donorSingle time donor

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