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Study of correlation between chronic stressor, biochemical markers and hematologic indices in Shahrekord Cohort

Ali Ahmadi1, Soghra Ahmadi Sodejani1, Reza Malekzadeh2

  • 1Modeling in Health Research Center and School of Public Health, Department of Epidemiology and Biostatistics, Shahrekord University of Medical Sciences, Shahrekord, Iran.

Diabetes & Metabolic Syndrome
|June 26, 2019
PubMed

Insights

This study found job security stress significantly impacts biochemical factors and hematologic indices. These findings aid in early detection of chronic stress consequences, particularly for preventing cardiovascular diseases.

Area of Science:

  • Public Health
  • Biochemistry
  • Hematology

Background:

  • Stress is a significant, modifiable risk factor for non-communicable diseases.
  • Understanding stress's impact on physiological markers is crucial for disease prevention.

Purpose of the Study:

  • To investigate the relationship between stress and biochemical factors.
  • To examine the association between stress and hematologic indices.

Main Methods:

  • Cross-sectional study utilizing data from the Shahrekord Cohort Study (SCS).
  • 1000 randomly selected participants from the SCS (2017-2018).
  • Stress assessed using the Questionnaire of Stressful Life Events; biochemical and hematologic indices measured via standard blood tests.

Main Results:

  • Job security emerged as a key stress dimension linked to numerous biochemical and hematologic markers.
  • Linear regression revealed significant correlations between stress and blood urea, liver enzymes (ALT, AST), education, marital status, and occupation.

Conclusions:

  • Exposure to stressors in the study population was notably high.
  • Results support using stress assessment for screening and early detection of chronic stress impacts, especially for cardiovascular disease prevention.
Abstract

Keywords:
Biochemical markersChronic stressorHematologic indicesPopulation-based cohort studyStress

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