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Discovery of a pyrazolo[1,5-a]pyrimidine derivative (MT-3014) as a highly selective PDE10A inhibitor via core

Yuuki Koizumi1, Yoshihito Tanaka1, Takehiko Matsumura2

  • 1Sohyaku. Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000 Kamoshida-cho, Aoba-ku, Yokohama 227-0033, Japan.

Bioorganic & Medicinal Chemistry
|June 26, 2019
PubMed

Keywords:
Conditioned avoidance response (CAR)Phosphodiesterase (PDE) 10APyrazolopyrimidineQuinoxalineSchizophrenia

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