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Updated: Jan 23, 2026

Analysis of Human Natural Killer Cell Metabolism
Published on: June 22, 2020
The nature of human IL-6
Anne Puel1,2, Jean-Laurent Casanova3,2,4,5,6
1Laboratory of Human Genetics of Infectious Diseases, Necker Branch, Institut National de la Santé et de la Recherche Médicale U1163, Necker Hospital for Sick Children, Paris, France anne.puel@inserm.fr.
None:
Countless functions have been attributed experimentally to IL-6. In this issue of JEM, Spencer et al. (https://doi.org/10.1084/jem.20190344) reveal essential, nonredundant functions of human IL-6. Patients with genetic deficiencies of the IL-6 receptor suffer from "hyper IgE syndrome."
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