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Updated: Jan 23, 2026

Transcutaneous Microcirculatory Imaging in Preterm Neonates
Published on: December 31, 2015
Turkish Neonatal Society guideline on parenteral nutrition in preterm infants
Canan Türkyılmaz1, Hülya Bilgen2, Nilgün Kültürsay3
1Division of Neonatology, Department of Pediatrics, Gazi University, Faculty of Medicine, Ankara, Turkey.
Insights
Early parenteral nutrition is crucial for preterm infants at risk of growth failure. This intensive nutritional support helps prevent negative neurodevelopmental effects and promotes healthy growth.
Area of Science:
- Neonatalogy
- Pediatric Nutrition
- Intensive Care Medicine
Background:
- Preterm infants, particularly very-low-birth-weight (VLBW) and extremely-low-birth-weight (ELBW) infants, are susceptible to postnatal growth failure.
- Inadequate nutrition during the extrauterine period can lead to significant long-term neurodevelopmental deficits.
- Enteral feeding is not always feasible for these vulnerable infants, necessitating alternative nutritional strategies.
Purpose of the Study:
- To highlight the critical role of early and intensive parenteral nutrition in managing preterm infants.
- To emphasize the importance of appropriate protein and energy delivery in preventing growth failure.
- To outline the key components and goals of parenteral nutrition in this population.
Main Methods:
- Initiation of intensive parenteral nutrition (PN) as a nutritional emergency when enteral feeding is not possible.
- Careful administration of protein, lipids, and glucose at appropriate doses to meet timely goals.
- Monitoring for achievement of positive protein balance and successful postnatal growth.
Main Results:
- Early PN initiation effectively prevents protein catabolism in preterm infants.
- Appropriate PN strategies facilitate the achievement of positive protein balance and support postnatal growth.
- Timely administration of macronutrients is essential for optimizing PN efficacy.
Conclusions:
- Intensive parenteral nutrition is a vital intervention for preterm infants facing nutritional challenges.
- Optimizing protein and energy delivery through PN is key to preventing extrauterine growth failure and its adverse neurodevelopmental consequences.
- The ultimate goal of PN should be to support growth while facilitating an early transition to mother's milk/enteral feeding.
Abstract:
Postnatal growth failure due to inappropriate and insufficient nutrition is a risk for preterm infants, especially for very-low-birth-weight or extremely-low-birth-weight infants. This extrauterine growth failure causes negative effects on long-term neurodevelopment. Early initiation of intensive parenteral nutrition with appropriate protein and energy supply is a nutritional emergency when enteral feeding cannot be achieved. This approach prevents protein catabolism and helps achievement of positive protein balance and postnatal growth. Protein, lipid, and glucose initiation with appropriate doses that reach timely goals constitute the major elements of parenteral nutrition. The transition to enteral nutrition with the mother's milk at the earliest convenience must be targeted in parenteral nutrition.
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