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Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
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Applications of arterial stiffness markers in peripheral arterial disease

Daniel Mendes-Pinto1,2, Maria da Glória Rodrigues-Machado2

  • 1Departamento de Cirurgia Vascular, Hospital Felício Rocho, Belo Horizonte, MG, Brasil.

Jornal Vascular Brasileiro
|June 26, 2019
PubMed

Insights

Assessing arterial stiffness, using measures like pulse wave velocity (PWV) and augmentation index (AIx), can help identify cardiovascular risk. This review explores its utility in patients with peripheral arterial disease.

Area of Science:

  • Cardiovascular Medicine
  • Vascular Biology
  • Clinical Physiology

Background:

  • Arterial stiffness, a marker of cardiovascular risk, impacts aortic and elastic artery function.
  • Key noninvasive measures include pulse wave velocity (PWV) and augmentation index (AIx).
  • Elevated PWV or AIx is linked to increased mortality in coronary disease and hemodialysis patients.

Purpose of the Study:

  • To review the applicability and clinical utility of arterial stiffness assessment.
  • To explore the association between arterial stiffness and peripheral arterial disease (PAD).

Main Methods:

  • Review of existing literature on arterial stiffness measures.
  • Analysis of noninvasive techniques for assessing PWV and AIx.
  • Examination of studies correlating arterial stiffness with cardiovascular outcomes.

Main Results:

  • Arterial stiffness measures (PWV, AIx) are established cardiovascular risk predictors.
  • Limited research currently exists on arterial stiffness in patients with PAD.
  • Noninvasive assessment of arterial stiffness is feasible in diverse patient groups.

Conclusions:

  • Arterial stiffness assessment offers potential for early cardiovascular risk identification in PAD patients.
  • Further research is warranted to establish the prognostic value of arterial stiffness in PAD.
  • Integrating arterial stiffness measures may enhance therapeutic strategies for PAD.

Keywords:
arterial stiffnessperipheral arterial diseasepulse wave velocity

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