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Crystals and calcification patterns in two lymph node calcifications.

T Sakae1, H Yamamoto

  • 1Department of Anatomy, Nihon University School of Dentistry at Matsudo, Chiba, Japan.

Journal of Oral Pathology
|October 1, 1987
PubMed
Summary
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This study analyzed calcified lymph nodes using advanced X-ray techniques. Researchers identified specific mineral compositions, including apatite and whitlockite, in submandibular and neck lymph node samples.

Area of Science:

  • Mineralogy
  • Pathology
  • Biomineralization

Background:

  • Calcified lymph nodes can present diagnostic challenges.
  • Understanding the mineral composition of calcifications is crucial for accurate diagnosis.

Purpose of the Study:

  • To characterize the mineral composition and micro-structure of calcified lymph nodes from submandibular and neck regions.
  • To investigate the relationship between mineral phases and tissue morphology.

Main Methods:

  • Micro-radiography
  • X-ray micro-diffraction
  • X-ray micro-analysis

Main Results:

  • Submandibular lymph node: Conglomerate texture with varying calcification degrees; contained well-crystallized apatite and minor whitlockite.

Related Experiment Videos

  • Neck lymph node: Islets with central translucent regions and outer calcified layers (spherulitic and smooth); frequently showed isolated, well-crystallized whitlockite in spherulitic areas.
  • X-ray micro-analysis revealed sporadic magnesium distribution, correlating with whitlockite occurrence.

    • Conclusions:

    • Calcified lymph nodes exhibit diverse micro-structures and mineral compositions.
    • Apatite and whitlockite are key mineral phases, with whitlockite's presence linked to magnesium distribution.
    • Advanced X-ray techniques are effective for detailed analysis of lymph node calcifications.