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Renal function and choroidal thickness using swept-source optical coherence tomography in diabetic patients
Antonio Manuel Garrido-Hermosilla1,2, Mariola Méndez-Muros3, Estanislao Gutiérrez-Sánchez1,2
1Department of Ophthalmology, Virgen Macarena University Hospital, Seville 41009, Spain.
Aim:
To assess the relationship between choroidal thickness and renal function in diabetic patients.
Methods:
Cross-sectional retrospective clinical study of 42 eyes of 21 ocular treatment-naïve diabetic patients. Demographic data included: age, sex, type and course of diabetes. Ocular data included: severity of diabetic retinopathy; retinal thickness at the central macular region, as well as choroidal thickness at the central and paracentral quadrants, using automatically generated maps by swept-source optical coherence tomography; presence of cystic macular edema; and ocular axial length (AXL). Lab-test parameters included: glycated hemoglobin (HbA1c), albuminuria, albumin/creatinine ratio in urine, and glomerular filtration rate.
Results:
A significant negative correlation was mainly observed between several choroidal thicknesses, age (P<0.020) and ocular AXL (P<0.030). On the contrary, a significant positive correlation was found between all choroidal thicknesses, HbA1c (P<0.035) and albuminuria (P<0.040).
Conclusion:
Choroidal thickness can represent an additional tool to help clinicians predicting the renal status in ocular treatment-naïve diabetic patients.
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