Related Experiment Video
Updated: Jan 23, 2026

In vivo Measurement of Knee Extensor Muscle Function in Mice
Published on: March 4, 2021
Self-reported and performance-based outcomes following medial patellofemoral ligament reconstruction indicate
Maria Biesert1,2,3, Anna Johansson4,5, Ioannis Kostogiannis4,5
1Department of Orthopaedics, Clinical Sciences, Skåne University Hospital, Malmö, Sweden. mbiesert@gmail.com.
Purpose:
To evaluate short- to midterm outcomes of medial patellofemoral ligament reconstruction (MPFL) using patient-reported outcome measures and functional testing.
Methods:
Twenty-four patients were examined regarding knee function after MPFL reconstruction, with a mean follow-up time of 45.3 ± 18.4 months since surgery. Knee function was evaluated using the Tegner score, VAS, the knee injury and osteoarthritis outcome score (KOOS), the Lysholm score, SF-36 and EQ-5D-3L as well as functional scores. A group of uninjured persons of the same age and same gender composition was used for comparison.
Results:
Eight (40%) patients managed to return to their pre-injury activity level. Five (25%) patients stated that they had experienced further patella dislocations after surgery but only two (10%) had sought medical help. Patients showed significantly poorer results in all PROMs compared to controls. The results obtained with SF-36 showed significant differences in physical health between the groups, but not in mental health. The functional performance test results showed overall poorer results for the patients versus controls: 11.5 sets for the square jump (6.7-15.7) versus 21 sets (18-26), 11.5 sets for the step-down test (6.5-15) versus 22 sets (18-26), and 77 cm for the single-leg hop for distance (32.2-110.5) versus 126 cm (115-37); all (P < 0.005).
Conclusions:
After MPFL reconstruction, patients do not regain normal knee function, as measured by PROMs and functional tests, compared to an uninjured control group. Patients should be informed about residual functional limitations despite improved stability.
Level Of Evidence:
III.
Related Concept Videos
Knee Joint
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
Limits on Trigonometric Functions
Ecological Succession
Limiting Reactant
RNA Stability
Nuclear Stability
To hold positively charged protons together...

