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Understanding Atrial Cardiopathy: an Under-Recognized Contributor to Cardioembolic Stroke

Michelle C Johansen1, Henrique Doria De Vasconcellos2, Rebecca F Gottesman3

  • 1Department of Neurology, The Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Phipps 4 Suite 446, Baltimore, MD, 21287, USA. mjohans3@jhmi.edu.

Current Treatment Options in Neurology
|June 26, 2019
PubMed

Insights

Cardioembolic stroke (CES) is a major cause of death, often linked to atrial fibrillation (AF). This review covers CES diagnosis, treatment, and future research directions for better patient outcomes.

Area of Science:

  • Neurology
  • Cardiology
  • Public Health

Background:

  • Ischemic stroke is a leading global cause of death.
  • Cardioembolic stroke (CES), primarily caused by atrial fibrillation (AF), contributes significantly to stroke morbidity and mortality.
  • The incidence of CES is expected to increase with an aging population.

Purpose of the Study:

  • To review current knowledge on the diagnosis and treatment of CES.
  • To discuss novel therapeutic options for CES.
  • To highlight areas for future research, including atrial cardiopathy.

Main Methods:

  • Literature review of recent advancements in CES and AF management.
  • Analysis of current treatment guidelines and emerging therapeutic strategies.
  • Identification of knowledge gaps in the diagnosis and treatment of embolic strokes of unknown source.

Main Results:

  • Significant advancements in monitoring and diagnosing AF have occurred.
  • Optimal secondary stroke prevention in AF patients with anticoagulation is established.
  • The management of embolic strokes without a clear source remains an area requiring further definition.

Conclusions:

  • Effective management of CES, particularly in the context of AF, is crucial.
  • Novel therapeutics are emerging for CES treatment.
  • Future research should focus on understanding conditions like atrial cardiopathy to improve CES management.
Abstract

Keywords:
Atrial cardiopathyCardioembolic strokeIschemic strokeStroke diagnosisStroke treatment

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