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Updated: Jan 23, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
[Epidemiology of multiple sclerosis in Spain]
N Perez-Carmona1, E Fernandez-Jover2, A P Sempere3
1Hospital de San Vicente del Raspeig, Alicante, Espana.
Introduction:
Multiple sclerosis is a chronic autoimmune, inflammatory and neurodegenerative disease of the central nervous system and the most common non-traumatic disabling neurological disease in young adults. In the latest decades, multiple sclerosis is increasing worldwide, especially in women. The latitudinal distribution has been progressively attenuated.
Aim:
To review the epidemiological studies of multiple sclerosis in Spain to verify if this worldwide trend also occurs in Spain.
Development:
We searched PubMed and Teseo databases using the search terms «epidemiology», «prevalence», «incidence», «multiple sclerosis» and «Spain». We selected articles published in Spanish and English between 1968 and 2018.
Conclusions:
Recent epidemiological studies confirm that Spain is a medium-high risk area for MS. The prevalence of MS has increased significantly throughout Spain in the latest years, especially in women, and recent studies show prevalence as high as 80-180 cases per 100,000.
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