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Pediatric Giant Cerebral Candida Abscess: A Case Report
Emre Bilgin1, Ali İhsan Ökten2, Yurdal Gezercan2
1Department of Neurosurgery, Adana City Training and Research Hospital, Adana, Turkey, dremreblgn@gmail.com.
Abstract:
Fungal infections of the central nervous system and pediatric brain abscess are rare but serious conditions in terms of morbidity and mortality that need immediate diagnosis and treatment. It can be seen in congenital or acquired immunosuppressed patients as opportunistic infections as well as in low-birth-weight, premature infants with ventriculoperitoneal shunt, external ventricular drainage, or with a history of craniotomy. Our aim is to emphasize the giant cerebral Candida abscess of a 13-month-old female infant who previously had eight ventriculoperitoneal shunt operations due to hydrocephalus. The patient was taken to pediatric emergency care with complaints of feeding difficulty and discomfort and was hospitalized due to the detection of an intracranial mass by contrast-enhanced brain tomography. After total excision of the mass with its capsule, the patient was pathologically diagnosed with Candida abscess, and the treatment was started. The patient was discharged by the end of the 6th week.
Insights
This case study highlights a rare giant cerebral Candida abscess in a 13-month-old infant. Prompt surgical removal and antifungal treatment led to successful recovery, emphasizing early diagnosis for pediatric brain infections.
Area of Science:
- Pediatric Neurology
- Infectious Diseases
- Neurosurgery
Background:
- Fungal central nervous system infections and pediatric brain abscesses are rare but critical conditions.
- These infections often occur in immunocompromised individuals or infants with neurosurgical interventions.
Observation:
- A 13-month-old female infant with a history of eight ventriculoperitoneal shunt operations presented with feeding difficulties.
- Contrast-enhanced brain tomography revealed a large intracranial mass.
Findings:
- Surgical excision of the mass was performed, followed by pathological diagnosis of Candida abscess.
- The infant received antifungal treatment and was discharged after six weeks.
Implications:
- This case underscores the importance of considering fungal infections in pediatric brain abscesses, especially in shunt-dependent hydrocephalus patients.
- Early diagnosis and aggressive management, including surgical resection and antifungal therapy, are crucial for favorable outcomes.
- Highlights the potential for opportunistic fungal infections in vulnerable pediatric populations.
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